Papillary Histiocytic and Mesothelial Hyperplasia of the Ovary Related to a Huge Uterus: A Case Report

Nodular histiocytic/mesothelial hyperplasia (NHMH) is a very rare condition. It generally thought to be associated with repeated mechanical or chemical stimulation. This study reported NHMH papillary growth pattern in the ovary following high-intensity focused ultrasound (HIFU) treatment for uterine leiomyoma and adenomyosis. A 48-year-old female, who had history of undergoing HIFU 7 times adenomyosis uterus 6 months ago, was referred hospital. After hysterectomy right salpingo-oophorectomy, patient confirmedly diagnosed nodular histiocytic mesothelial ovary. benign reactive inflammatory lesion mesothelium mimicking malignancy must kept mind avoid unnecessary treatment.